Bispidine as a helix inducing scaffold: examples of helically folded linear peptides.

نویسندگان

  • V Haridas
  • Sandhya Sadanandan
  • M V S Gopalakrishna
  • M B Bijesh
  • Ram P Verma
  • Srinivas Chinthalapalli
  • Ashutosh Shandilya
چکیده

We designed and synthesized bispidine-anchored peptides and showed that these peptides as small as (containing four chiral α-amino acid residues) adopt a right handed helical conformation. Bispidine anchored linear peptide adopts a helical conformation in solution and in the solid state.

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عنوان ژورنال:
  • Chemical communications

دوره 49 93  شماره 

صفحات  -

تاریخ انتشار 2013